On modern operating systems (Windows 10/11 and macOS), you can double-click an ISO file to "mount" it. Your computer will treat it as if you just inserted a physical DVD into a disc drive.
The very first, groundbreaking short. The Yankee Doodle Mouse (1943): The first Oscar winner.
If you want to optimize your setup for this collection, let me know: What or device you plan to use for playback