If you are looking to get the absolute best experience on modern hardware, I can also provide tips on: Configuring the game for 4K resolution Enabling the best graphical mods (reShade) Fixing common mouse input lag Share public link
Max Payne 3 - PC Game Optimisation Guides | GeForce - NVIDIA
For players trying to enjoy Max Payne 3 on handheld PCs or Linux distributions via Valve's Proton translation layer, the v1.0.0.272 executable is mandatory. The multimedia playback updates included in this version align cleanly with Valve's Proton Experimental and Proton GE fixes. This removes the need for complex, manual command-line tweaks or third-party video codecs just to get the story mode working. How to Verify and Update Your Game Version
The Max Payne 3 update 100216 100272.exe is a significant patch that improves the game's performance, fixes several bugs and glitches, and adds new features. Players who experience issues with the game or want to enhance their gaming experience should install the update. With its improved performance, increased stability, and new content, the Max Payne 3 update 100216 100272.exe is a must-have for any Max Payne 3 player.
Even with the latest official update, certain legacy issues may remain. You can further optimize your experience with these community-vetted steps: Max Payne 3 PC Title Update v1.0.0.272 Notes