Every season of Prison Break delivers a unique chapter in the overarching narrative of structural engineer Michael Scofield and his brother Lincoln Burrows. Below is an in-depth breakdown of each season, including episode counts and key plot structures. Season 1 (2005–2006) | 22 Episodes : Fox River State Penitentiary.

Focuses on Michael Scofield deliberately getting incarcerated at Fox River State Penitentiary to break out his brother, Lincoln Burrows, who is on death row for a crime he didn’t commit.

The brothers shift from defense to offense. Homeland Security recruits the team to track down "Scylla," a digital data module that serves as the black book for The Company. This season moves away from traditional prison walls and functions heavily as an espionage action thriller. Prison Break: The Final Break (Special TV Movie)